4UMM: The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning

PDB ID: 4UMMDownload
MMDB ID: 167296
PDB Deposition Date: 2014/5/19
Updated in MMDB: 2018/10
Experimental Method:
electron microscopy
Resolution: 11.6  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4UMM: hexameric; determined by software (PISA)
Molecular Components in 4UMM
Label Count Molecule
Proteins (4 molecules)
1
Ecr-usp
Molecule annotation
1
Ecdysone Receptor
Molecule annotation
1
Gene Regulation Protein
Molecule annotation
1
Ecdysone Receptor
Molecule annotation
Nucleotides(2 molecules)
1
5'-d(*cp*ap*ap*gp*gp*gp*tp*tp*cp*ap*ap*tp*gp*cp *ap*cp*tp*tp*gp*tp)-3'
Molecule annotation
1
5'-d(*dgp*ap*cp*ap*ap*gp*tp*gp*cp*ap*tp*tp*gp*dap *ap*cp*cp*cp*tp*t)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINEL-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE
2
1
2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303