5BVO: Fragment-based discovery of potent and selective DDR1/2 inhibitors

PDB ID: 5BVODownload
MMDB ID: 131533
PDB Deposition Date: 2015/6/5
Updated in MMDB: 2015/08
Experimental Method:
x-ray diffraction
Resolution: 1.98  Å
Source Organism:
Similar Structures:
Biological Unit for 5BVO: monomeric; determined by software (PISA)
Molecular Components in 5BVO
Label Count Molecule
Protein (1 molecule)
1
Epithelial Discoidin Domain-containing Receptor 1
(Gene symbol: DDR1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
7
IODIDE IONIODIDE ION
2
1
N-(5-{(1S)-1-[(5-fluoro-1,3-benzoxazol-2-yl)amino]ethyl}-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamideN-(5-{(1S)-1-[(5-fluoro-1,3-benzoxazol-2-yl)amino]ethyl}-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303