5H7O: Crystal structure of DJ-101 in complex with tubulin protein

PDB ID: 5H7ODownload
MMDB ID: 157163
PDB Deposition Date: 2016/11/20
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Rattus norvegicus▼
Similar Structures:
Biological Unit for 5H7O: hexameric; determined by author
Molecular Components in 5H7O
Label Count Molecule
Proteins (6 molecules)
2
Tubulin Alpha-1b Chain
Molecule annotation
2
Tubulin Beta-2b Chain
Molecule annotation
1
Stathmin-4
Molecule annotation
1
Tubulin Tyrosine Ligase
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
GUANOSINE-5'-TRIPHOSPHATE (Link to PubChem not yet available)GUANOSINE-5'-TRIPHOSPHATE
2
4
MAGNESIUM ION (Link to PubChem not yet available)MAGNESIUM ION
3
2
CALCIUM ION (Link to PubChem not yet available)CALCIUM ION
4
1
GLYCEROL (Link to PubChem not yet available)GLYCEROL
5
1
GUANOSINE-5'-DIPHOSPHATE (Link to PubChem not yet available)GUANOSINE-5'-DIPHOSPHATE
6
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID (Link to PubChem not yet available)2-(N-MORPHOLINO)-ETHANESULFONIC ACID
7
2
2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine (Link to PubChem not yet available)2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine
8
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER (Link to PubChem not yet available)PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303