National Center for
Biotechnology Information

5V8F: Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1

PDB ID:

MMDB ID:

186872

PDB Deposition Date:

2017/3/21

Updated in MMDB:

2020/04

Experimental Method:

electron microscopy

Resolution:

3.9 Å

Source Organism:

Saccharomyces cerevisiae S288C▼

Taxonomy	Molecule
Saccharomyces cerevisiae S288C	2, 3, 4, 5, 6, 7, 8, 9, A, B, C, E, D, F
synthetic construct	M, N

Similar Structures:

Biological Unit for 5V8F: hexadecameric; determined by author

Molecular Components in 5V8F
Label	Count	Molecule
Proteins (14 molecules)
2	1	DNA Replication Licensing Factor Mcm2
3	1	DNA Replication Licensing Factor Mcm3
4	1	DNA Replication Licensing Factor Mcm4
5	1	Minichromosome Maintenance Protein 5
6	1	DNA Replication Licensing Factor Mcm6
7	1	DNA Replication Licensing Factor Mcm7
8	1	Cell Division Cycle Protein Cdt1
9	1	Cell Division Control Protein 6
A	1	Origin Recognition Complex Subunit 1
B	1	Origin Recognition Complex Subunit 2
C	1	Origin Recognition Complex Subunit 3
E	1	Origin Recognition Complex Subunit 5
D	1	Origin Recognition Complex Subunit 4
F	1	Origin Recognition Complex Subunit 6
Nucleotides(2 molecules)
M	1	DNA (39-mer)
N	1	DNA (39-mer)
Chemicals and Non-standard biopolymers (8 molecules)
1	8	PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER

* Click molecule labels to explore molecular sequence information.

Citing MMDB