6E53: Structure of TERT in complex with a novel telomerase inhibitor

PDB ID: 6E53Download
MMDB ID: 173591
PDB Deposition Date: 2018/7/19
Updated in MMDB: 2019/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6E53: dimeric; determined by author and by software (PISA)
Molecular Components in 6E53
Label Count Molecule
Protein (1 molecule)
1
Telomerase Reverse Transcriptase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
E
1
RNA/DNA hairpin
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
methyl 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-D-erythro-pentofuranosyl}-1H-indole-5-carboxylatemethyl 1-{2-deoxy-5-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-D-erythro-pentofuranosyl}-1H-indole-5-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303