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6ECR:
The human methylenetetrahydrofolate dehydrogenase/cyclohydrolase (FolD) complexed with NADP
PDB ID:
6ECR
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MMDB ID:
173597
PDB Deposition Date:
2018/8/8
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6ECR: dimeric; determined by author and by software (PISA)
Molecular Components in 6ECR
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Methylenetetrahydrofolate Dehydrogenase Cyclohydrolase
(Gene symbol:
MTHFD1
)
Chemicals and Non-standard biopolymers (3 molecules)
1
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
ACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303