6HVJ: Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 3

PDB ID: 6HVJDownload
MMDB ID: 168741
PDB Deposition Date: 2018/10/11
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.28  Å
Source Organism:
Similar Structures:
Biological Unit for 6HVJ: monomeric; determined by author and by software (PISA)
Molecular Components in 6HVJ
Label Count Molecule
Protein (1 molecule)
1
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Gene symbol: PFKFB3)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
8-(3-methyl-1-benzofuran-5-yl)-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine8-(3-methyl-1-benzofuran-5-yl)-~{N}-(4-methylsulfonylpyridin-3-yl)quinoxalin-6-amine
2
1
FRUCTOSE-6-PHOSPHATEFRUCTOSE-6-PHOSPHATE
3
1
PHOSPHATE IONPHOSPHATE ION
4
1
CITRATE ANIONCITRATE ANION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303