6IBZ: Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 7

PDB ID: 6IBZDownload
MMDB ID: 170719
PDB Deposition Date: 2018/12/1
Updated in MMDB: 2019/02
Experimental Method:
x-ray diffraction
Resolution: 2.44  Å
Source Organism:
Similar Structures:
Biological Unit for 6IBZ: monomeric; determined by author and by software (PISA)
Molecular Components in 6IBZ
Label Count Molecule
Protein (1 molecule)
1
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
(Gene symbol: PFKFB3)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
PHOSPHATE IONPHOSPHATE ION
2
1
CITRATE ANIONCITRATE ANION
3
1
2-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-(pyrimidin-5-ylmethyl)benzenesulfonamide2-[[8-(1-methylindol-6-yl)quinoxalin-6-yl]amino]-~{N}-(pyrimidin-5-ylmethyl)benzenesulfonamide
4
1
6-O-phosphono-beta-D-fructofuranose6-O-phosphono-beta-D-fructofuranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303