6JOK: Crystal structure of PDGFRA in complex with sunitinib by soaking

PDB ID: 6JOKDownload
MMDB ID: 185572
PDB Deposition Date: 2019/3/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6JOK: monomeric; determined by author and by software (PISA)
Molecular Components in 6JOK
Label Count Molecule
Protein (1 molecule)
1
Platelet-derived Growth Factor Receptor Alpha
(Gene symbol: PDGFRA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamideN-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide
2
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303