6M4U: Crystal structure of FKBP-FRB T2098L mutant in complex with rapamycin

PDB ID: 6M4UDownload
MMDB ID: 191593
PDB Deposition Date: 2020/3/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6M4U: dimeric; determined by author
Molecular Components in 6M4U
Label Count Molecule
Proteins (2 molecules)
1
Peptidyl-prolyl Cis-trans Isomerase Fkbp1a
(Gene symbol: FKBP1A)
Molecule annotation
1
Serine/threonine-protein Kinase Mtor
(Gene symbol: MTOR)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
2
RAPAMYCIN IMMUNOSUPPRESSANT DRUGRAPAMYCIN IMMUNOSUPPRESSANT DRUG
2
11
ZINC IONZINC ION
3
5
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303