6O0O: crystal structure of BCL-2 G101V mutation with S55746

PDB ID: 6O0ODownload
MMDB ID: 175654
PDB Deposition Date: 2019/2/17
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.998  Å
Source Organism:
Similar Structures:
Biological Unit for 6O0O: monomeric; determined by author and by software (PISA)
Molecular Components in 6O0O
Label Count Molecule
Protein (1 molecule)
1
Apoptosis Regulator Bcl-2,bcl-2-like Protein 1,apoptosis Regulator Bcl-2
(Gene symbol: BCL2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide~{N}-(4-hydroxyphenyl)-3-[6-[[(3~{S})-3-(morpholin-4-ylmethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]-1,3-benzodioxol-5-yl]-~{N}-phenyl-5,6,7,8-tetrahydroindolizine-1-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303