6R4O: Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein

PDB ID: 6R4ODownload
MMDB ID: 175228
PDB Deposition Date: 2019/3/22
Updated in MMDB: 2019/11
Experimental Method:
electron microscopy
Resolution: 4.2  Å
Source Organism:
Similar Structures:
Biological Unit for 6R4O: dimeric; determined by author and by software (PISA)
Molecular Components in 6R4O
Label Count Molecule
Proteins (2 molecules)
1
Adenylate Cyclase 9
(Gene symbol: ADCY9)
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
(Gene symbol: GNAS)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE
2
1
FORSKOLINFORSKOLIN
3
2
MANGANESE (II) IONMANGANESE (II) ION
4
1
5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
5
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303