6S7B: Crystal structure of CARM1 in complex with inhibitor UM249

PDB ID: 6S7BDownload
MMDB ID: 184877
PDB Deposition Date: 2019/7/4
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 2.659  Å
Source Organism:
Homo sapiens▼
Similar Structures:
Biological Unit for 6S7B: dimeric; determined by author and by software (PISA)
Molecular Components in 6S7B
Label Count Molecule
Proteins (2 molecules)
2
Histone-arginine Methyltransferase Carm1
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
1-[4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azanylpropyl)amino]butyl]guanidine1-[4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(3-azanylpropyl)amino]butyl]guanidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303