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6SC2:
Structure of the dynein-2 complex; IFT-train bound model
PDB ID:
6SC2
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MMDB ID:
179212
PDB Deposition Date:
2019/7/23
Updated in MMDB:
2019/09
Experimental Method:
electron microscopy
Resolution:
3.9 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6SC2: 14-meric; determined by author
Molecular Components in 6SC2
Label
Count
Molecule
Proteins (14 molecules)
A
1
O6-alkylguanine-dna Alkyltransferase Mutant,dync2h1 Variant Protein,o6-alkylguanine-dna Alkyltransferase Mutant,cytoplasmic Dynein 2 Heavy Chain 1,dync2h1 Variant Protein,dync2h1 Variant Protein,dync2h1 Variant Protein
B
1
O6-alkylguanine-dna Alkyltransferase Mutant,dync2h1 Variant Protein,o6-alkylguanine-dna Alkyltransferase Mutant,cytoplasmic Dynein 2 Heavy Chain 1,dync2h1 Variant Protein,dync2h1 Variant Protein,dync2h1 Variant Protein
C
1
WD Repeat-containing Protein 60
(Gene symbol:
WDR60
)
D
1
WD Repeat-containing Protein 34
(Gene symbol:
WDR34
)
E
F
2
Cytoplasmic Dynein 2 Light Intermediate Chain 1
(Gene symbol:
DYNC2LI1
)
G
H
2
Dynein Light Chain Roadblock-type 1
(Gene symbol:
DYNLRB1
)
I
J
K
L
M
N
6
Dynein Light Chain 1, Cytoplasmic
(Gene symbol:
DYNLL1
)
Chemicals and Non-standard biopolymers (10 molecules)
1
6
ADENOSINE-5'-DIPHOSPHATE
2
2
ADENOSINE-5'-TRIPHOSPHATE
3
2
MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303