6UJ4: Discovery of fragment-inspired heterocyclic benzenesulfonmides as inhibitors of the WDR5-MYC interaction

PDB ID: 6UJ4Download
MMDB ID: 186468
PDB Deposition Date: 2019/10/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.53  Å
Source Organism:
Similar Structures:
Biological Unit for 6UJ4: monomeric; determined by author and by software (PISA)
Molecular Components in 6UJ4
Label Count Molecule
Protein (1 molecule)
1
WD Repeat Domain 5
(Gene symbol: WDR5)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-bromo-3-chloro-N-(1-cyclopentyl-2-methyl-1H-imidazol-4-yl)-2-hydroxybenzene-1-sulfonamide5-bromo-3-chloro-N-(1-cyclopentyl-2-methyl-1H-imidazol-4-yl)-2-hydroxybenzene-1-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303