7CVN: The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase

PDB ID: 7CVNDownload
MMDB ID: 193235
PDB Deposition Date: 2020/8/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.75  Å
Source Organism:
Similar Structures:
Biological Unit for 7CVN: tetrameric; determined by author and by software (PISA)
Molecular Components in 7CVN
Label Count Molecule
Proteins (4 molecules)
4
Fructose-1,6-bisphosphatase 1
(Gene symbol: FBP1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide
2
4
1,6-di-O-phosphono-beta-D-fructofuranose1,6-di-O-phosphono-beta-D-fructofuranose
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303