7E1X: Cryo-EM structure of hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis complexIII and Mycobacterium smegmatis complexIV in presence of TB47

PDB ID: 7E1XDownload
MMDB ID: 208105
PDB Deposition Date: 2021/2/3
Updated in MMDB: 2021/11
Experimental Method:
electron microscopy
Resolution: 2.93  Å
Source Organism:
Mycolicibacterium smegmatis MC2 51▼
Similar Structures:
Biological Unit for 7E1X: eicosameric; determined by software (PISA)
Molecular Components in 7E1X
Label Count Molecule
Proteins (20 molecules)
2
Cytochrome C Oxidase Subunit 2
Molecule annotation
2
Cytochrome C Oxidase Subunit 1
Molecule annotation
2
Cytochrome C Oxidase Subunit 3
Molecule annotation
2
Cytochrome C Oxidase Polypeptide 4
Molecule annotation
2
Cytochrome C Oxidase Subunit Ctaj
Molecule annotation
2
Uncharacterized Protein Msmeg_4692/msmei_4575
Molecule annotation
2
Prokaryotic Respiratory Supercomplex Associate Factor 1 Prsaf1
Molecule annotation
2
Cytochrome BC1 Complex Cytochrome B Subunit
Molecule annotation
2
Cytochrome BC1 Complex Rieske Iron-sulfur Subunit
Molecule annotation
2
Cytochrome BC1 Complex Cytochrome C Subunit
Molecule annotation
Chemicals and Non-standard biopolymers (59 molecules)
1
8
COPPER (II) ION (Link to PubChem not yet available)COPPER (II) ION
2
17
CARDIOLIPIN (Link to PubChem not yet available)CARDIOLIPIN
3
4
PALMITIC ACID (Link to PubChem not yet available)PALMITIC ACID
4
4
HEME-A (Link to PubChem not yet available)HEME-A
5
2
(2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate (Link to PubChem not yet available)(2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate
6
4
PROTOPORPHYRIN IX CONTAINING FE (Link to PubChem not yet available)PROTOPORPHYRIN IX CONTAINING FE
7
8
MENAQUINONE-9 (Link to PubChem not yet available)MENAQUINONE-9
8
2
5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide (Link to PubChem not yet available)5-methoxy-2-methyl-~{N}-[[4-[4-[4-(trifluoromethyloxy)phenyl]piperidin-1-yl]phenyl]methyl]pyrazolo[1,5-a]pyridine-3-carboxamide
9
2
FE2/S2 (INORGANIC) CLUSTER (Link to PubChem not yet available)FE2/S2 (INORGANIC) CLUSTER
10
4
(2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate (Link to PubChem not yet available)(2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate
11
4
HEME C (Link to PubChem not yet available)HEME C
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303