7JVN: Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor Compound 24

PDB ID: 7JVNDownload
MMDB ID: 193242
PDB Deposition Date: 2020/8/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.917  Å
Source Organism:
Similar Structures:
Biological Unit for 7JVN: monomeric; determined by author and by software (PISA)
Molecular Components in 7JVN
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Phosphatase Non-receptor Type 11
(Gene symbol: PTPN11)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine6-(4-amino-4-methylpiperidin-1-yl)-3-[(2,3-dichlorophenyl)sulfanyl]pyrazin-2-amine
2
4
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303