7MIH: Human CTPS2 bound to inhibitor R80

PDB ID: 7MIHDownload
MMDB ID: 207555
PDB Deposition Date: 2021/4/16
Updated in MMDB: 2021/10
Experimental Method:
electron microscopy
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 7MIH: tetrameric; determined by author
Molecular Components in 7MIH
Label Count Molecule
Proteins (4 molecules)
4
CTP Synthase 2
(Gene symbol: CTPS2)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
N-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamideN-(1-{2-[(cyclopropanesulfonyl)amino]-1,3-thiazol-4-yl}cyclopropyl)-5-(6-ethoxypyrazin-2-yl)pyridine-2-carboxamide
2
4
URIDINE 5'-TRIPHOSPHATEURIDINE 5'-TRIPHOSPHATE
3
4
GLUTAMINEGLUTAMINE
4
4
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303