7MR5: Crystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-052

PDB ID: 7MR5Download
MMDB ID: 215474
PDB Deposition Date: 2021/5/7
Updated in MMDB: 2022/05
Experimental Method:
x-ray diffraction
Resolution: 1.82  Å
Source Organism:
Similar Structures:
Molecular Components in 7MR5
Label Count Molecule
Proteins (2 molecules)
2
Bromodomain-containing Protein 4
(Gene symbol: BRD4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
N,N'-{oxybis[(ethane-2,1-diyl)oxy(1-oxoethane-2,1-diyl)piperidine-1,4-diyl]}bis{4-[(4-{4-chloro-3-[(2-methylpropane-2-sulfonyl)amino]anilino}-5-methylpyrimidin-2-yl)amino]-2-fluorobenzamide}(Link to PubChem not yet available)N,N'-{oxybis[(ethane-2,1-diyl)oxy(1-oxoethane-2,1-diyl)piperidine-1,4-diyl]}bis{4-[(4-{4-chloro-3-[(2-methylpropane-2-sulfonyl)amino]anilino}-5-methylpyrimidin-2-yl)amino]-2-fluorobenzamide}
2
1,2-ETHANEDIOL(Link to PubChem not yet available)1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.

Citing MMDB