7P2R: Crystal structure of mouse PRMT6 in complex with inhibitor EML980

PDB ID: 7P2RDownload
MMDB ID: 215297
PDB Deposition Date: 2021/7/6
Updated in MMDB: 2022/09
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7P2R: dimeric; determined by author and by software (PISA)
Molecular Components in 7P2R
Label Count Molecule
Proteins (2 molecules)
2
Protein Arginine N-methyltransferase 6
(Gene symbol: Prmt6)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
methyl 6-[4-[[N-[2-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl]carbamimidoyl]amino]butylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylatemethyl 6-[4-[[N-[2-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl]carbamimidoyl]amino]butylcarbamoylamino]-4-oxidanyl-naphthalene-2-carboxylate
2
1
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303