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1PTH
The Structural Basis Of Aspirin Activity Inferred From The Crystal Structure Of Inactivated Prostaglandin H2 Synthase
Biological unit 1: dimeric
Source organism: Ovis aries
Number of proteins:
2 (PROSTAGLANDIN H2 SYNTHASE-1 )
Protein molecule
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PROSTAGLANDIN H2 SYNTHASE-1
Number of chemicals:
14 (B-Octylglucoside (2),Protoporphyrin Ix Containi... )
Similar Structures (175)help
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Showing 1 to 10 out of 175 selected structures help
      PDB ID Description Taxonomy Aligned Protein RMSD Aligned Residues Sequence Identity
1
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1PGE
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH P-(2'-IODO-5'-THENOYL)HYDROTROPIC ACID (IODOSUPROFEN)
Ovis aries
2 0.22Å 1102 100%
2
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1PGG
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), TRANS MODEL
Ovis aries
2 0.26Å 1102 100%
3
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1CQE
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEX WITH FLURBIPROFEN
Ovis aries
2 0.27Å 1102 100%
4
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1PGF
PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), CIS MODEL
Ovis aries
2 0.27Å 1102 100%
5
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1EQG
THE 2.6 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH IBUPROFEN
Ovis aries
2 0.36Å 1102 100%
6
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1EQH
THE 2.7 ANGSTROM MODEL OF OVINE COX-1 COMPLEXED WITH FLURBIPROFEN
Ovis aries
2 0.37Å 1102 100%
7
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1PRH
The X-Ray Crystal Structure Of The Membrane Protein Prostaglandin H2 Synthase-1
Ovis aries
2 0.37Å 1102 99%
8
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2AYL
2.0 Angstrom Crystal Structure of Manganese Protoporphyrin IX-reconstituted Ovine Prostaglandin H2 Synthase-1 Complexed With Flurbiprofen
Ovis aries
2 0.37Å 1102 100%
9
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1HT8
THE 2.7 ANGSTROM RESOLUTION MODEL OF OVINE COX-1 COMPLEXED WITH ALCLOFENAC
Ovis aries
2 0.38Å 1102 100%
10
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4O1Z
Crystal Structure of Ovine Cyclooxygenase-1 Complex with Meloxicam
Ovis aries
2 0.40Å 1102 100%
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{"1":"PROSTAGLANDIN H2 SYNTHASE-1","2":"PROSTAGLANDIN H2 SYNTHASE-1"}
Citing VAST
Thomas Madej, Aron Marchler-Bauer, Christopher Lanczycki, Dachuan Zhang, Stephen H Bryant "Biological Assembly Comparison With VAST" Methods Mol. Biol. 2020(2112):175-186
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?Original VAST
Original VAST finds structures that are similar to individual protein molecules, or individual 3D domains, in your query structure. Select a protein molecule ("chain") or 3D domain of interest from the table below to view a list of other proteins or domains that have a similar 3D shape. In contrast to VAST+, which focuses on the default biological unit, Original VAST lists all protein molecules in the asymmetric unit of the query structure.