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Accession: PRJNA383982 ID: 383982

Human gammaherpesvirus 8

Identification of symmetric methylation of histone H4 arginine 3 on KSHV genome (iSLKBac16WT ChIP-Seq)

The objective of this study was to identify the symmetric methylation sites on KSHV genome during latency and lytic reactivation Overall design: KSHV infected iSLKBac16WT cells were induced with doxycycline for 24h to trigger the lytic reactivation, cells were crosslinked and subjected for chromatin isolation and sonication. ChIP assay was performed using specific antibodies.
AccessionPRJNA383982; GEO: GSE98087
Data TypeEpigenomics
ScopeMultiisolate
OrganismHuman gammaherpesvirus 8[Taxonomy ID: 37296]
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus; Human gammaherpesvirus 8
PublicationsStrahan RC et al., "KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation.", PLoS Pathog, 2017 Jul;13(7):e1006482
SubmissionRegistration date: 24-Apr-2017
Verma Lab, Microbiology and Immunology, University of Nevada, Reno
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Mbases30
Data volume, Mbytes9

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    Human gammaherpesvirus 8
    Identification of symmetric methylation of histone H4 arginine 3 on KSHV genome (iSLKBac16WT ChIP-Seq)
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