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Accession: PRJNA445346 ID: 445346

human metagenome

16S rRNA gene amplicon sequencing of patients with colorectal cancer

A collection of 16S rRNA gene amplicon sequences from patients with colorectal cancer, and technical controls. Samples come from stool, mucosa, tissue biopsies and tumor biopsies.
AccessionPRJNA445346
Data TypeTargeted Locus (Loci)
ScopeEnvironment
Organismhuman metagenome[Taxonomy ID: 646099]
unclassified sequences; metagenomes; organismal metagenomes; human metagenome
Publications
  • Hale VL et al., "Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers.", Genome Med, 2018 Oct 31;10(1):78
  • Hale VL et al., "Synthesis of multi-omic data and community metabolic models reveals insights into the role of hydrogen sulfide in colon cancer.", Methods, 2018 Oct 1;149:59-68
Grants
  • "Mayo Clinic Metabolomics Resource Core" (Grant ID U24 DK100469 , National Institutes of Health)
  • "Mayo Center for Cell Signaling in Gastroenterology" (Grant ID P30 DK084567 , National Institutes of Health)
  • "Time lapse to cancer: defining transition from polyp to colorectal cancer (PQ14)" (Grant ID R01 CA170357, National Cancer Institute)
  • "Microbial Metabolic Toxicity Drives Colon Cancer" (Grant ID R01 CA179243, National Cancer Institute)
SubmissionRegistration date: 23-Mar-2018
Mayo Clinic
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments1420
Publications
PubMed2
PMC2
Other datasets
BioSample1420
SRA Data Details
ParameterValue
Data volume, Gbases37
Data volume, Mbytes21122

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    16S rRNA gene amplicon sequencing of patients with colorectal cancer
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