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Accession: PRJNA590131 ID: 590131

Mitochondrial Dysfunction Induces Epigenetic Dysregulation by H3K27 Hyperacetylation to Perturb Active Enhancers in Parkinson’s Disease Models (Norway rat)

See Genome Information for Rattus norvegicus
We aim to explore the predominant mitochondrial dysfunctions in PD, with a focus on how altering the histone code contributes to PD pathogenesis. More...
AccessionPRJNA590131; GEO: GSE140524
ScopeMultiisolate
OrganismRattus norvegicus[Taxonomy ID: 10116]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus
PublicationsHuang M et al., "Mitochondrial dysfunction-induced H3K27 hyperacetylation perturbs enhancers in Parkinson's disease.", JCI Insight, 2021 Sep 8;6(17)
SubmissionRegistration date: 18-Nov-2019
Environmental Health and Engineering, Johns Hopkins University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Publications
PubMed1
PMC1
Other datasets
BioSample24
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2233
SRA Data Details
ParameterValue
Data volume, Gbases87
Data volume, Mbytes32657

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