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Genome Information for Rattus norvegicus
We report changes in the fetal brain cortical transcriptome after oxytocin-induced aberrant uterine contractility using unbiased RNA-seq analysis.
Overall design: We performed RNA-seq analysis to examine differential gene expression in the E21 fetal cortex 24 h after maternal administration of either oxytocin (100 mcg/kg i.v; n = 5 pups from 5 independent dams) or same volume of saline (5 pups from 5 independent mothers). With an FDR adjusted p < 0.05, only mt-nd2 was determined to be significantly differentially expressed in the fetal brain after maternal oxytocin.
| Accession | PRJNA609567; GEO: GSE146155 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus |
| Publications | Palanisamy A et al., "In utero exposure to transient ischemia-hypoxemia promotes long-term neurodevelopmental abnormalities in male rat offspring.", JCI Insight, 2020 May 21;5(10) |
| Submission | Registration date: 1-Mar-2020
Anesthesiology, Washington University School of Medicine |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 10 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 10 |
| GEO DataSets | 1 |