See
Genome Information for Caenorhabditis elegans
Mutant alleles of KIN17 (dxbp-1) and PRCC (prcc-1) were identifed in a forward genetic screen for suppressors of cryptic splice site activation
Overall design: Strains with cryptic splicing suppressor alleles in dxbp-1 ((M107I) or (K23N)) or prcc-1 ((I371F) or (null)) along with NMD mutant allele smg-4(az152) were compared to strains carrying the smg-4 mutant allele alone to identify changes in native gene alternative splicing
| Accession | PRJNA738508; GEO: GSE178335 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Caenorhabditis elegans[Taxonomy ID: 6239] Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis; Caenorhabditis elegans |
| Publications | Suzuki JMNGL et al., "A genetic screen in C. elegans reveals roles for KIN17 and PRCC in maintaining 5' splice site identity.", PLoS Genet, 2022 Feb;18(2):e1010028 |
| Grants | - "Uncovering Mechanisms of 5' Splice Site Fidelity" (Grant ID R01 GM135221, National Institute of General Medical Sciences)
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| Submission | Registration date: 16-Jun-2021
Zahler Lab, MCD Biology, UC Santa Cruz |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 15 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 15 |
| GEO DataSets | 1 |