RNA seq analysis of MC38CEA cells with diminished ... (ID 751377) - BioProject

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Accession: PRJNA751377 ID: 751377

RNA seq analysis of MC38CEA cells with diminished ADAM17 expression due to Crispr/Cas9 gene editing or control cells (house mouse)

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The goal of this study was to compare transcriptomes of cells with reduced and normal levels of ADAM17, unstimulated or stimulated with IL1b and IFNg Overall design: The cells were electroporated with Cas9 mRNA and after four hours electroporated with in vitro transcribed sgRNAs targeting Adam17 or EGFP (control). More...

Accession	PRJNA751377; GEO: GSE181271
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Czarnek M et al., "shRNAs targeting mouse Adam10 diminish cell response to proinflammatory stimuli independently of Adam10 silencing.", Biol Open, 2022 Mar 15;11(3)
Submission	Registration date: 1-Aug-2021 Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	12
Publications
PubMed	1
PMC	1
Other datasets
BioSample	12
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	5

SRA Data Details

Parameter	Value
Data volume, Gbases	38
Data volume, Mbytes	28641

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RNA seq analysis of MC38CEA cells with diminished ADAM17 expression due to Crispr/Cas9 gene editing or control cells (house mouse)

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