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Genome Information for Mus musculus
We tested they hypothesis that hepatocyte SIRT1 mediates transcriptomic changes induced by hepatocyte-specific NAMPT overexpression
Overall design: We overexpressed NAMPT in western diet-fed WT and SIRT1 liver-specific knockout mice for 12wk and subjected liver tissue to high-throughput RNA sequencing
Accession | PRJNA764444; GEO: GSE184394 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
Publications | Higgins CB et al., "SIRT1 selectively exerts the metabolic protective effects of hepatocyte nicotinamide phosphoribosyltransferase.", Nat Commun, 2022 Feb 28;13(1):1074 |
Submission | Registration date: 18-Sep-2021 Brian DeBosch, Pediatrics and Cell Biology & Physiology, Washington University School of Medicine |
Relevance | Model Organism |
Project Data:
Resource Name | Number of Links |
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Sequence data |
SRA Experiments | 25 |
Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
BioSample | 25 |
GEO DataSets | 1 |