KRAS allelic imbalance drives a MAPK dependent tum... (ID 797286) - BioProject

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Accession: PRJNA797286 ID: 797286

KRAS allelic imbalance drives a MAPK dependent tumour initiation programme inefficient at rewiring the tumour microenvironment to provoke metastasis (house mouse)

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66518 additional projects are related by organism.

Murine small intestinal tumours, adjacent normal tissues and tumour organoids, following Kras mutation under the control of VilCreER, alone or in combination with p53 and Notch mutation, in the presence or absence of a wild type Kras allele. More...

Accession	PRJNA797286; GEO: GSE193703
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Najumudeen AK et al., "KRAS allelic imbalance drives tumour initiation yet suppresses metastasis in colorectal cancer in vivo.", Nat Commun, 2024 Jan 2;15(1):100
Submission	Registration date: 14-Jan-2022 CRUK Beatson Institute
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	25
Publications
PubMed	1
PMC	1
Other datasets
BioSample	25
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	2

SRA Data Details

Parameter	Value
Data volume, Gbases	74
Data volume, Mbytes	31159

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KRAS allelic imbalance drives a MAPK dependent tumour initiation programme inefficient at rewiring the tumour microenvironment to provoke metastasis (house mouse)

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