BioProject

In the present study, we described how SARS-CoV-2 can silently infect palatine tonsils and adenoids in from asymptomatic children without a history of recent infection. More...

In the present study, we described how SARS-CoV-2 can silently infect palatine tonsils and adenoids in from asymptomatic children without a history of recent infection. We studied 48 children undergoing tonsillectomy due to snoring/OSA or recurrent tonsillitis to treat tonsillar hypertrophy between 2020 and 2021. None of the children had experienced any symptom suggestive of acute viral upper airway infections in the month prior to surgery. Briefly, nasal cytobrush (NC), nasal wash (NW) and tonsillar tissue fragments obtained at surgery post-tonsillectomy were tested by RT-PCR, immunohistochemistry (IHC), flow cytometry, neutralization assay and Nanopore Sequencing. Less...