HDAC6 deacetylates IDH1 to regulate the homeostasi... (ID 980202) - BioProject

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Accession: PRJNA980202 ID: 980202

HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells [WGBS-seq] (house mouse)

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66502 additional projects are related by organism.

In order to further explore the mechanism by which increased 5hmC inhibits expansion of LSK cells from Hdac6-/- murine primary BM cells, we performed WGBS-seq and oxWGBS-seq analysis using LSK cells isolated from Hdac6-/- and WT mice. More...

Accession	PRJNA980202; GEO: GSE234147
Data Type	Epigenomics
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Yang J et al., "HDAC6 deacetylates IDH1 to promote the homeostasis of hematopoietic stem and progenitor cells.", EMBO Rep, 2023 Oct 9;24(10):e56009
Submission	Registration date: 5-Jun-2023 nankai university
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	4
Publications
PubMed	1
Other datasets
BioSample	4
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	8

SRA Data Details

Parameter	Value
Data volume, Gbases	289
Data volume, Mbytes	99978

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HDAC6 deacetylates IDH1 to regulate the homeostasis of hematopoietic stem/progenitor cells [WGBS-seq] (house mouse)

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