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Genome Information for Danio rerio
Pbx homeodomain proteins have been implicated in the regulation of gene expression during muscle development. Whether Pbx proteins are required broadly for the regulation of muscle gene expression or are required for the expression of a specific subset of muscle gene expression is not known. We employed microarrays to determine the requirements for Pbx proteins during zebrafish development.
Keywords: developmental time course analysis
Overall design: Total RNA samples from control and pbx2-MO;pbx4-MO embryos were collected at two developmental stages: 10 somites and 18 somites. Their expression profiles were analyzed using Affymetrix zebrafish genome arrays, and the differentially hybridized genes were determined to be significant according to a FDR<0.05.
| Accession | PRJNA101487; GEO: GSE8428 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Danio rerio[Taxonomy ID: 7955] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio; Danio rerio |
| Publications | Maves L et al., "Pbx homeodomain proteins direct Myod activity to promote fast-muscle differentiation.", Development, 2007 Sep;134(18):3371-82 |
| Submission | Registration date: 11-Jul-2007
Tapscott, Human Biology, Fred Hutchinson CRC |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
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| Data volume, Spots | 187404 |
| Data volume, Processed Mbytes | 5 |
| Data volume, Supplementary Mbytes | 27 |