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Accession: PRJNA102543 ID: 102543

Mus musculus (house mouse)

Gene expression profiles of striatum and cerebellum from knock-in mouse model of Huntington's disease

See Genome Information for Mus musculus
Huntington’s disease (HD) involves marked early neurodegeneration in the striatum whereas the cerebellum is relatively spared despite the ubiquitous expression of full-length mutant huntingtin, implying that inherent tissue-specific differences determine susceptibility to the HD CAG mutation. More...
AccessionPRJNA102543; GEO: GSE9038
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsFossale E et al., "Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.", Hum Mol Genet, 2011 Nov 1;20(21):4258-67
SubmissionRegistration date: 23-Aug-2011
Center for Human Genetic Reseaarch, Massachusetts General Hospital
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots1082424
Data volume, Processed Mbytes19
Data volume, Supplementary Mbytes90

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    Mus musculus
    Gene expression profiles of striatum and cerebellum from knock-in mouse model of Huntington's disease
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