Mus musculus (ID 118389) - BioProject

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Accession: PRJNA118389 ID: 118389

Mus musculus (house mouse)

Analysis of altered gene expressions in valproate-treated Disc1-L100P mutant mice

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66518 additional projects are related by organism.

Microarray analysis revealed that changes in genes expressions are brain region-dependent; expression of several genes are affected by point mutation L100P, which was verified by RT-PCR (Lcn2, Cyr61, Slc6a12, Slc40a1, Egr2), a few genes are affected by genotype and valproate (Dusp1 and Purb), suggesting their role in valproate-induced benificial effect on sensorimotor gaiting in Disc1-L100P mutant mice. More...

Accession	PRJNA118389; GEO: GSE17735
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Lipina TV et al., "Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3.", Synapse, 2011 Mar;65(3):234-48
Submission	Registration date: 24-Nov-2009 Ontario Institute for Cancer Research
Relevance	Model Organism

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Resource Name	Number of Links
Publications
PubMed	1
PMC	1
Other datasets
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Spots	1773093
Data volume, Processed Mbytes	43
Data volume, Supplementary Mbytes	4401

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Mus musculus (house mouse)

Analysis of altered gene expressions in valproate-treated Disc1-L100P mutant mice

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