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Accession: PRJNA171162 ID: 171162

Mus musculus (house mouse)

Decrease of Parkin and CD36 expression and body weight correlate with an increase of non-esterified fatty acids in a mouse model for TDP-43 pathology

See Genome Information for Mus musculus
TDP-43-coding mutations are found among ALS patients. In oder to express human mutant TDP-43 protein in the mouse under the control of the endogenous Tardp promoter, we have generate a mouse line wit 300% elevated TDP-43 level. More...
AccessionPRJNA171162; GEO: GSE39585
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsStribl C et al., "Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.", J Biol Chem, 2014 Apr 11;289(15):10769-10784
SubmissionRegistration date: 23-Jul-2012
Gene Regulation & Epigenetics, Institute of Experimental Genetics, Helmholtz Zentrum M√ľnchen GmbH
RelevanceModel Organism
Project Data:
Resource NameNumber
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Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots513940
Data volume, Processed Mbytes15
Data volume, Supplementary Mbytes4

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