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Accession: PRJNA189547 ID: 189547

Mus musculus (house mouse)

Expression data from Adriamycin-treated Emu-myc; Suv39h1-/- B-cell lymphoma

See Genome Information for Mus musculus
Oncogene-induced senescence (OIS), a terminal cell cycle block countering (pre)neoplastic lesions, is characterised on the molecular level by trimethylated histone H3 lysine 9 (h3K9me3), a transcriptionally repressive chromatin mark linked to silencing of S-phase-promoting genes. More...
AccessionPRJNA189547; GEO: GSE44355
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications
  • Milanovic M et al., "Senescence-associated reprogramming promotes cancer stemness.", Nature, 2018 Jan 4;553(7686):96-100
  • Dörr JR et al., "Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.", Nature, 2013 Sep 19;501(7467):421-5
SubmissionRegistration date: 15-Feb-2013
Clemens Schmitt, Hematology and Oncology, Charite University Medicine, Berlin
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed2
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots451010
Data volume, Processed Mbytes9
Data volume, Supplementary Mbytes27

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    Mus musculus
    Expression data from Adriamycin-treated Emu-myc; Suv39h1-/- B-cell lymphoma
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