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Accession: PRJNA202976 ID: 202976

Mus musculus (house mouse)

SIRT1 but not its increased expression is essential for lifespan extension in caloric restricted mice.

See Genome Information for Mus musculus
The SIRT1 deacetylase is one of the best-studied potential mediators of some of the anti-aging effects of calorie restriction (CR); but its role in CR-dependent lifespan extension has not been demonstrated. More...
AccessionPRJNA202976; GEO: GSE46895
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsMercken EM et al., "SIRT1 but not its increased expression is essential for lifespan extension in caloric-restricted mice.", Aging Cell, 2014 Feb;13(1):193-6
SubmissionRegistration date: 14-May-2013
Computational Biology Core, Laboratory of Genetics and Genomics, NIA-IRP, NIH
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots462546
Data volume, Processed Mbytes15
Data volume, Supplementary Mbytes3

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