This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA230510; GEO: GSE52947 |
| Type | Umbrella project |
| Publications | Butovsky O et al., "Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice.", Ann Neurol, 2015 Jan;77(1):75-99 |
| Submission | Registration date: 3-Dec-2013
Dr. Oleg Butovsky, Center of Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 20 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 20 |
| GEO DataSets | 10 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 49850 |
| Data volume, Processed Mbytes | 8 |
| Data volume, Supplementary Mbytes | 17 |
| Parameter | Value |
|---|
| Data volume, Gbases | 34 |
| Data volume, Mbytes | 25441 |
This project encompasses the following 9 sub-projects:
| Project Type | Number of Projects |
| Other | 8 |
BioProject
accession | Organism | Title |
|---|
| PRJNA230491 | Homo sapiens | Immune gene profile in lumbar spinal cord homogenate of healthy controls and ALS (Dr. Oleg Butovsky, Center...) | | PRJNA230490 | Homo sapiens | miRNA profile in lumbar spinal cord homogenate from healthy controls and ALS (Dr. Oleg Butovsky, Center...) | | PRJNA230551 | Homo sapiens | MG447 profile of lumbar spinal cord homogenate from healthy controls and ALS (Dr. Oleg Butovsky, Center...) | | PRJNA230488 | Mus musculus | miRNA profile in lumbar spinal cord homogenate of SOD-miR155 Tg mice (Dr. Oleg Butovsky, Center...) | | PRJNA230489 | Mus musculus | Inflammation gene profile of sc-microglia in SOD mice (Dr. Oleg Butovsky, Center...) | | PRJNA230487 | Mus musculus | MG400 profile of microglia from SOD miR155-KO mice (Dr. Oleg Butovsky, Center...) | | PRJNA230493 | Mus musculus | MG400 profile of spinal cord microglia during disease progression in SOD mice (Dr. Oleg Butovsky, Center...) | | PRJNA230492 | Mus musculus | miRNA profile in SOD-155 microglia (Dr. Oleg Butovsky, Center...) |
Less... |
| Transcriptome or Gene expression | 1 |
BioProject
accession | Organism | Title |
|---|
| PRJNA230511 | Homo sapiens | miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] (Dr. Oleg Butovsky, Center...) |
|