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Accession: PRJNA240233 ID: 240233

Homo sapiens (human)

Inhibiting tankyrases sensitizes KRAS mutant cancer cells to MEK inhibitors by FGFR2 feedback signaling

See Genome Information for Homo sapiens
Tankyrases (TNKS) play roles in Wnt signaling, telomere homeostasis and mitosis, offering attractive targets for anti-cancer treatment. More...
AccessionPRJNA240233; GEO: GSE55624
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsSchoumacher M et al., "Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling.", Cancer Res, 2014 Jun 15;74(12):3294-305
SubmissionRegistration date: 5-Mar-2014
Novartis
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots984150
Data volume, Processed Mbytes15
Data volume, Supplementary Mbytes93

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