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Accession: PRJNA310602 ID: 310602

Homo sapiens (human)

Human neural stem cells transduced with oncogenic elements associated with aggressive medulloblastoma

See Genome Information for Homo sapiens
Human neural stem and progenitor cells transformed with c-MYC, dominant-negative p53, constitutively active AKT and hTERT formed tumors in mice that recapitulated Group 3 medulloblastoma in terms of pathology and expression profile Overall design: Isogenic model systems and mouse xenografts
AccessionPRJNA310602; GEO: GSE77475
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsHanaford AR et al., "DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.", Clin Cancer Res, 2016 Aug 1;22(15):3903-14
SubmissionRegistration date: 2-Feb-2016
Moores Cancer Center, UCSD
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots328290
Data volume, Processed Mbytes9
Data volume, Supplementary Mbytes13

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    Human neural stem cells transduced with oncogenic elements associated with aggressive medulloblastoma
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