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Genome Information for Homo sapiens
Human neural stem and progenitor cells transformed with c-MYC, dominant-negative p53, constitutively active AKT and hTERT formed tumors in mice that recapitulated Group 3 medulloblastoma in terms of pathology and expression profile
Overall design: Isogenic model systems and mouse xenografts
Accession | PRJNA310602; GEO: GSE77475 |
Data Type | Transcriptome or Gene expression |
Scope | Multiisolate |
Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
Publications | Hanaford AR et al., "DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets.", Clin Cancer Res, 2016 Aug 1;22(15):3903-14 |
Submission | Registration date: 2-Feb-2016 Moores Cancer Center, UCSD |
Relevance | Medical |
Project Data:
Resource Name | Number of Links |
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Publications |
PubMed | 1 |
PMC | 1 |
Other datasets |
GEO DataSets | 1 |
GEO Data DetailsParameter | Value |
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Data volume, Spots | 328290 |
Data volume, Processed Mbytes | 9 |
Data volume, Supplementary Mbytes | 13 |