See
Genome Information for Homo sapiens
Follicular Lymphoma primary cells (FL) were treated with the PI3K delta inhibitor idelalisib (500nM, 48h) in the presence or absence of follicular dendritic cells
We used microarrays to uncover the mechanisms underlying mechanism of resistance and sensitivity of FL to idelalisib
Overall design: Global RNA expression was done in five primary FL biopsies treated in vitro with idelalisib in monoculture or cocultured with follicular dendritic cells
| Accession | PRJNA541941; GEO: GSE130918 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Serrat N et al., "PI3Kδ inhibition reshapes follicular lymphoma-immune microenvironment cross talk and unleashes the activity of venetoclax.", Blood Adv, 2020 Sep 8;4(17):4217-4231 |
| Submission | Registration date: 8-May-2019
Hemato-oncology, IDIBAPS |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 616460 |
| Data volume, Processed Mbytes | 14 |
| Data volume, Supplementary Mbytes | 40 |