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Accession: PRJNA551688 ID: 551688

miR-221-3p drives the Shift of M2-Macrophage to a Pro-Inflammatory Function by Modulating JAK3/STAT3 Signaling and is Increased in Rheumatoid Arthritis (human)

See Genome Information for Homo sapiens
We performed a transcriptome analysis of M2 macrophages generated in vitro from monocytes isolated from peripheral blood of healthy donors, and studied the effect of miR-221-3p mimic transfection and stimulation with LPS. More...
AccessionPRJNA551688; GEO: GSE133527
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsQuero L et al., "miR-221-3p Drives the Shift of M2-Macrophages to a Pro-Inflammatory Function by Suppressing JAK3/STAT3 Activation.", Front Immunol, 2019;10:3087
SubmissionRegistration date: 28-Jun-2019
Experimental rheumatology, Biomedicine, University of Basel
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Publications
PubMed1
PMC1
Other datasets
BioSample20
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases73
Data volume, Mbytes28029

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