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Genome Information for Homo sapiens
RNA-seq analysis was performed to identify key signaling responding to PCI-24781 in MDA-MB-231
Overall design: Four independent sample groups were exposed to PCI-24781 and controls were treated with DMSO for 24 h and 48 h (DMSO-treated groups: DMSO 24 h, DMSO 48 h; PCI-24781-treated groups: 100 nM 24 h; 100 nM 48 h; 200 nM 24 h; 200 nM 48 h) in MDA-MB-231 and were analyzed through RNA-seq.
| Accession | PRJNA630975; GEO: GSE150038 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Yang T et al., "The histone deacetylase inhibitor PCI-24781 impairs calcium influx and inhibits proliferation and metastasis in breast cancer.", Theranostics, 2021;11(5):2058-2076 |
| Submission | Registration date: 7-May-2020
National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 1 |