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Accession: PRJNA98039 ID: 98039

Mus musculus (house mouse)

Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity

See Genome Information for Mus musculus
To examine the effects of disrupting the AML1/ETO MYND-SMRT interaction with the W692A substitution on AML1/ETO function, the global gene expression profile of mouse bone marrow LSK cells transduced with GFP was compared to that of cells transduced with either wild-type AML1/ETO or AML1/ETO harboring the W692A substitution in the MYND domain. More...
AccessionPRJNA98039; GEO: GSE7324
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLiu Y et al., "Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity.", Cancer Cell, 2007 Jun;11(6):483-97
SubmissionRegistration date: 21-Mar-2007
Speck Lab, Biochemistry, Dartmouth Medical School
RelevanceModel Organism
Project Data:
Resource NameNumber
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Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots451010
Data volume, Processed Mbytes13
Data volume, Supplementary Mbytes29

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    Mus musculus
    Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity
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