H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells [twins] - - GEO DataSets

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H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells [twins]

(Submitter supplied) In differentiated cells, aging is associated with hypermethylation of DNA regions enriched in repressive histone posttranslational modifications. However, the chromatin marks associated with changes in DNA methylation in adult stem cells during lifetime are still largely unknown. Here, DNA methylation profiling of mesenchymal stem cells obtained from individuals aged 2 to 92 identified 18735 hypermethylated and 45407 hypomethylated CpG sites associated with aging. more...

Organism:: Homo sapiens

Type:: Methylation profiling by array

Platform:: GPL13534
24 Samples

Download data: TXT

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Accession:: GSE52113

ID:: 200052113

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