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Contribution of Foxp3 to the Treg signature

(Submitter supplied) The transcription factor Foxp3 is usually considered the master regulator for the CD4+CD25+ "Treg" lineage, which plays a key role in controlling immune and autoimmune responses, and is characterized by a unique transcriptional signature. We have performed a meta-analysis of this signature in Treg cells in several conditions to delineate the elements that can be ascribed to T cell activation, TGFbeta signaling, or Foxp3 itself. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
52 Samples
Download data: CEL
Series
Accession:
GSE7460
ID:
200007460

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