GEO DataSets for BioProject (Select 102091) - GEO DataSets

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Items: 2

Select item 2000087901.

Comparative analysis of gene expression in A/J CS vs Air lungs.

(Submitter supplied) We hypothesize that gene expression in the CS-exposed lungs of this strain (A/J) of mice would be able to give clues about the molecular mechanism of emphysema development, thus contributing to this phenotype. More specifically, although imbalance in oxidants/antioxidants and proteinase/antiproteinase pathways drives the pathogenesis of COPD, the molecular mechanisms involved in the development of emphysema are poorly understood. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS3548
Platform:: GPL1261
22 Samples

Download data: CEL, EXP

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Accession:: GSE8790

ID:: 200008790

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 35482.

Cigarette smoke-induced pulmonary emphysema model

Analysis of lungs of A/J animals exposed to cigarette smoke (CS) for up to 6 months. A/J animals chronically exposed to CS develop pulmonary emphysema (PE). Results provide insight into the molecular mechanisms underlying the initiation and development of PE.