GEO DataSets for BioProject (Select 125963) - GEO DataSets

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Items: 2

Select item 2000215211.

Immature cell populations and an erythropoiesis gene expression signature in systemic juvenile idiopathic arthritis: Implications for pathogenesis

(Submitter supplied) Objective. Previous observations suggest that active systemic juvenile idiopathic arthritis (sJIA) is associated with a prominent erythropoiesis gene expression signature. The aim of this study was to determine the association of this signature with peripheral blood mononuclear cell (PBMC) subpopulations and its specificity for sJIA as compared to related conditions. 125 patients with JIA (18 sJIA and 107 non-sJIA) and 29 controls were studied. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4267
Platform:: GPL570
154 Samples

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Accession:: GSE21521

ID:: 200021521

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 42672.

Systemic juvenile idiopathic arthritis and non-systemic JIA subtypes: peripheral blood mononuclear cells

Analysis of PBMCs from patients with systemic juvenile idiopathic arthritis (sJIA) or non-sJIA. sJIA patients have significantly increased expansion of immature PBMC subpopulations, including CD34+ cells. Results provide insight into molecular mechanisms underlying sJIA pathogenesis.