Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing - - GEO DataSets

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Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing

(Submitter supplied) We report that delta cells are Sox9 descendants that expand at the periphery of the regenerating islets following partial pancreatectomy. We further characterize regeneration-driven heterogeneity of beta cells at a single-cell resolution, demonstrating sub-populations of ER-stressed, proliferating and highly-functioning beta-cells. We further systematically map sub populations of beta-cells that are paired with other endocrine cell types. more...

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL19057
6 Samples

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Accession:: GSE183788

ID:: 200183788

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